Informations sur le produit
- 1,2-Dideoxy-2'-ethylamino-a-D-glucopyranoso-[2,1-d]-2'-thiazoline(3aR,5R,6S,7R,7aR)-2-(Ethylamino)-3 a,6,7,7a-tetrahydro-5-(hydroxy methyl)-5H-pyrano[3
- 2-d]thiazole-6,7-diol
Thiamet G inhibits β-N-acetylglucosaminidase, also known as O-GlcNAcase (OGA), which cleaves the O-linked glycans from glycoproteins. Interferes with O-GlcNAc cycling and leads to the accumulation of O-GlcNAcylated proteins. Thiamet G elicits neuroprotective effects by modulating microglia/macrophages and inhibiting hyperphosphorylation of the microtubule-associated protein tau in models of stroke and Alzheimer’s disease. Thiamet G also has implications on diabetes and cardiovascular pathologies.
Thiamet G is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.
Propriétés chimiques
Question d’ordre technique sur : 3D-BT300146 Thiamet G - Bio-X ™
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