Coelenterazine, native

CAS : 55779-48-1

Ref. 3D-C-7001

Informations sur le produit

• Nom: Coelenterazine, native
• Synonymes: 2-(p-Hydroxybenzyl)-6-(p-hydroxyphenyl)-8-benzyl-imidazo[1,2-a]pyrazin-3-(7H)-one
• Marque: Biosynth
• Description: Coelenterazine is the substrate for the enzymes Renilla luciferase, Gaussia luciferase and other luciferase enzymes. Marine organisms like squids, shrimps, fish and jellyfish use coelenterazine to produce spectacular bioluminescence (in analogy with insects which utilize firefly luciferine). Today, coelenterazine is used in numerous applications like immunoassays, ELISA, monitoring of reporter genes, chemiluminescence detection of superoxide anion and peroxynitritein cells or tissues. The substrate is also used in bioluminescence resonance energy transfer (BRET), HTS and protein based methods for Calcium detection. The isolation and structure determination of coelenterazine was reported independently by two different groups in the seventies who discovered the molecule in sea pansy (Renilla reniformis) and in the cnidarian Aequorea victoria, respectively. Interestingly it was also found that the luminescent jellyfish Aequorea victoria does not produce coelenterazine itself but it rather assimilates it through ingestion of small preys like shrimps and copepods.This product Coelenterazine, native, which is provided as a powder, is identical in quality and chemistry to our product Coelenterazine, native, dried.

Propriétés chimiques

• Masse moléculaire: 423.48 g/mol
• Formule: C₂₆H₂₁N₃O₃
• Degré de pureté: Min. 95 Area-%