2-(4-Pyridyl)-1,3-benzothiazole

CAS : 2295-38-7

Ref. 3D-CAA29538

Informations sur le produit

• Nom: 2-(4-Pyridyl)-1,3-benzothiazole
• Synonymes: 2-(4-Pyridinyl)benzothiazole, 2-(4-Pyridyl)benzothiazole, 2-(Pyridin-4-yl)benzo[d]thiazole, 2-(Pyridin-4-yl)benzothiazole, Benzothiazole, 2-(4-Pyridinyl)-, Benzothiazole, 2-(4-pyridyl)-, H 223, NSC 38712

Description

2-(4-Pyridyl)-1,3-benzothiazole is a pancreatic carcinogen. It has been shown to be an important factor in the development of pancreatic cancer. 2-(4-Pyridyl)-1,3-benzothiazole is a ligand for the nuclear receptor PPARγ and can activate this receptor by binding to it. Activated PPARγ then regulates gene expression and protein synthesis, leading to tumorigenesis. In addition, 2-(4-Pyridyl)-1,3-benzothiazole has been shown to inhibit the activity of methionine synthase and increase the amount of homocysteine in cells. This inhibition ultimately leads to cell death by increasing reactive oxygen species that can cause DNA damage or inhibit protein synthesis.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 212.27 g/mol
• Formule: C₁₂H₈N₂S
• Degré de pureté: Min. 95%