(S)-Diethyl 2-(4-(methylamino)benzamido)pentanedioate

CAS : 2378-95-2

Ref. 3D-CAA37895

Informations sur le produit

• Nom: (S)-Diethyl 2-(4-(methylamino)benzamido)pentanedioate
• Synonymes: 1,5-Diethyl N-[4-(methylamino)benzoyl]-<span class="text-smallcaps">L</span>-glutamate, <span class="text-smallcaps">L</span>-Glutamic acid, N-[4-(methylamino)benzoyl]-, 1,5-diethyl ester, <span class="text-smallcaps">L</span>-Glutamic acid, N-[4-(methylamino)benzoyl]-, diethyl ester, Diethyl N-(p-N-methylaminobenzoyl)glutamate, Diethyl N-[4-(methylamino)benzoyl]-<span class="text-smallcaps">L</span>-glutamate, Glutamic acid, N-[p-(methylamino)benzoyl]-, diethyl ester, Glutamic acid, N-[p-(methylamino)benzoyl]-, diethyl ester, <span class="text-smallcaps">L</span>-, N-(4-Methylaminobenzoyl)-L-Glutamic Acid Diethylester, N-(p-Methylaminobenzoyl)glutamic acid diethyl ester, diethyl N-[4-(methylamino)benzoyl]-L-glutamate, diethyl N-[4-(methylamino)benzoyl]glutamate, p-Methylaminobenzoylglutamic acid diethyl ester, L-Glutamic acid, N-[4-(methylamino)benzoyl]-, 1,5-diethyl ester, Glutamic acid, N-[p-(methylamino)benzoyl]-, diethyl ester, L-, 1,5-Diethyl N-[4-(methylamino)benzoyl]-L-glutamate, L-Glutamic acid, N-[4-(methylamino)benzoyl]-, diethyl ester

Description

Diethyl 2-(4-(methylamino)benzamido)pentanedioate is a prodrug that is metabolized to (S)-diethyl 2-(4-aminobenzamido)pentanedioate, which inhibits the enzyme dihydrofolate reductase. This prevents the synthesis of tetrahydrofolate, an essential cofactor in the synthesis of nucleic acids and amino acids. The antibiotic has been shown to be active against bacteria such as Mycobacterium tuberculosis and Staphylococcus aureus, but not against mammalian cells.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 336.38 g/mol
• Formule: C₁₇H₂₄N₂O₅
• Degré de pureté: Min. 95%