Sorivudine

CAS : 77181-69-2

Ref. 3D-CDA18169

Informations sur le produit

• Nom: Sorivudine
• Synonymes: (+)-1-beta-D-Arabinofuranosyl-5-((E)-2-bromovinyl)uracil, (E)-1-beta-D-Arabinofuranosyl-5-(2-bromoethenyl)-2,4(1H,3H)-pyrimidinedione, (E)-5-(2-Bromovinyl)-1-(β-<span class="text-smallcaps">D</span>-arabinofuranosyl)uracil, (E)-5-(2-Bromovinyl)-1-beta-D-arabinofuranosyluracil, (E)-5-(2-Bromovinyl)uridine, 1-beta-D-Arabinofuranosyl-(E)-5-(2-bromovinyl)uracil, 1-beta-D-arabinofuranosyl-5-[(E)-2-bromoethenyl]pyrimidine-2,4(1H,3H)-dione, 1-β-<span class="text-smallcaps">D</span>-Arabinofuranosyl-(E)-5-(2-bromovinyl)uracil, 1-β-<span class="text-smallcaps">D</span>-Arabinofuranosyl-5-(2-bromovinyl)uracil, 1-β-<span class="text-smallcaps">D</span>-Arabinofuranosyl-5-[(1E)-2-bromoethenyl]-2,4(1H,3H)-pyrimidinedione, 2,4(1H,3H)-Pyrimidinedione, 1-beta-D-arabinofuranosyl-5-(2-bromoethenyl)-, (E)-, 2,4(1H,3H)-Pyrimidinedione, 1-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-5-(2-bromoethenyl)-, (E)-, 2,4(1H,3H)-Pyrimidinedione, 1-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-5-[(1E)-2-bromoethenyl]-, 5-Bromovinyl-araU, Arabinosyl (E)-5-(2-bromovinyl)uracil, BV-Ara-U, BVaraU, Bravavir, Bromovinyluridine, Brovavir, Ccris 5285, Dru-0136, Sorivudina, Sorivudina [INN-Spanish], Sorivudine [USAN:INN:BAN:JAN], Sorivudinum, Sorivudinum [INN-Latin], Sq-32756, Usevir, Yn-72

Description

Sorivudine is a nucleoside analog that is used to treat HIV. It has been shown to be effective in treating solid tumours, such as lung cancer and breast cancer. Sorivudine binds to the DNA polymerase and inhibits the synthesis of viral DNA, which prevents the virus from replicating. Sorivudine is an acyclic nucleoside phosphonate that has a prodrug form (sorivudine monophosphate). This drug is taken orally and needs to be activated by intracellular phosphorylation. Sorivudine can cause side effects such as headache, nausea, vomiting, fatigue, fever, cough, pain in joints or muscles, loss of appetite, rash or other skin reactions. These are most likely due to its effect on dextran sulfate (a sugar molecule) and calcium pantothenate (a B vitamin). These side effects are more common in patients with AIDS who have taken sorivudine

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 349.13 g/mol
• Formule: C₁₁H₁₃BrN₂O₆
• Degré de pureté: Min. 95%