2-(2,2-Diphenylacetyl)-6-methoxy-5-phenylmethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid

CAS : 152362-51-1

Ref. 3D-CGA36251

Informations sur le produit

• Nom: 2-(2,2-Diphenylacetyl)-6-methoxy-5-phenylmethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid
• Marque: Biosynth
• Description: 2-(2,2-Diphenylacetyl)-6-methoxy-5-phenylmethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid (AMG 827) is a potent angiotensin system inhibitor that is chemically related to losartan. AMG 827 has been shown to inhibit the proliferation of lung cells and target cells in vitro. It has been shown to be effective against viruses such as herpes simplex virus type 1 and 2. The enzyme inhibitors are active against nonselective kinases including protein kinase C, cyclooxygenase, and phospholipases. These agents have also been shown to have immunosuppressive properties. AMG 827 also inhibits cell growth in a line of human lung cancer cells (A549). Clinical trials are currently underway for the treatment of emphysema with this drug.

Propriétés chimiques

• Masse moléculaire: 507.6 g/mol
• Formule: C₃₂H₂₉NO₅
• Degré de pureté: Min. 95%