SB 399885 Hydrochloride

CAS : 402713-81-9

Ref. 3D-CRA71381

Informations sur le produit

• Nom: SB 399885 Hydrochloride

Description

SB 399885 Hydrochloride is a selective 5-HT2A receptor antagonist, which has been shown to reduce food intake and body weight in animal models. SB 399885 Hydrochloride is also a potent and selective 5-HT6 receptor antagonist, with an IC50 of 0.4 nM. SB 399885 Hydrochloride inhibits the activation of the paraventricular nucleus (PVN) neurons by 5-hydroxytryptamine (5-HT) and attenuates the activation of the nucleus accumbens (NAc) neurons by 5-HT. SB 399885 Hydrochloride also blocks the appetitive responses induced by stimulation of the PVN or NAc by 5-HT.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 446.35 g/mol
• Formule: C₁₈H₂₁Cl₂N₃O₄S•HCl
• Degré de pureté: Min. 95%