Feleucin-B01

Ref. 3D-CRB1000052

Informations sur le produit

• Nom: Feleucin-B01
• Synonymes: H-FLGLLGSLL-NH2
• Marque: Biosynth
• Description: Feleucin-B01 was recently identified from the skin secretion of the toad Bombina orientalis with a role in preventing the host from bacterial infection. Synthetic feleucin-B01 shows limited antimicrobial activity against a reference Gram-positive bacterium and is ineffective against the Gram-negative and yeast strains. The mode of action of the non-apeptide is lysis of the bacterial membrane resulting in rapid bacterial death. Feleucin-B01 shows a limited role in the secreted host defences which is complemented by the range of alternate antimicrobial peptides (AMP) also excreted. The amphipathic feleucin-B01 sequence is being studied as a template to hopefully generate more potent synthetic versions with a broader range of activity.

Propriétés chimiques

• Masse moléculaire: 931.17 g/mol