RGD Peptide GRGDSPK

CAS : 111119-28-9

Ref. 3D-CRB1000549

Informations sur le produit

• Nom: RGD Peptide GRGDSPK
• Synonymes: H-GRGDSPK-OH, H-Gly-Arg-Gly-Asp-Ser-Pro-Lys-OH, glycyl-N~5~-(diaminomethylidene)-L-ornithylglycyl-L-alpha-aspartyl-L-seryl-L-prolyl-L-lysine

Description

GRGDSPK is the sequence found in cell binding region of fibronectin and many other proteins. The sequence, referred to as RGD, is critical for facilitating cell adhesion.-RGD peptide is an adhesive peptide which can be used in a biomaterial context to attach cells to a range of materials. RGD has many applications including as an antigen for integrin adhesion of thymocytes to thymic epithelial cells. RGD can be used as a blocking peptide to study bacteria and fibronectin. RGD can also be used on collagen-coated plates for study of integrins' role in progenitor cell differentiation. Delivery of RGD peptide inhibits bone mineralization in a dose-dependent manner so GRGDSPK is used to study the role of integrins in bone formation. The presence of RGD peptide dramatically alters bone morphology, with a disruption of osteoblast and mineralized matrix organisation. RGD is a vital research tool in bone formation and integrin.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 715.4 g/mol
• Formule: C₂₈H₄₉N₁₁O₁₁
• Degré de pureté: Min. 95%
• Couleur/Forme: Powder