Cyclo(RGDfK)

Ref. 3D-CRB1001046

Informations sur le produit

• Nom: Cyclo(RGDfK)
• Synonymes: [Bbc]RGD(dF)K Cyclo(RGDfK) where f is D-Phenylalanine Cyclo(Arg-Gly-Asp-[D-Phe]-Lys)where D-Phe is D-Phenylalanine c(RGDfK) c(-RGDfK)
• Marque: Biosynth
• Description: The cyclic pentapeptide cyclo(Arg-Gly-Asp-[D-Phe]-Lys) is a highly potent and selective inhibitor for the alphavβ3 integrin receptor. A related compound, cyclo(Arg-Gly-Asp-[D-Phe]-Val), is a promising anticancer drug candidate- it inhibits angiogenesis and induces apoptosis in vascular cells.Cyclic RGD-containing peptides are selective antagonists of integrins, proteins that play important roles in cell-cell and cell-matrix interactions. In a suitably labelled form, these peptides may serve as useful tools for diagnostic imaging and peptide targeted therapy of some types of cancer.

Propriétés chimiques

• Masse moléculaire: 603.3 g/mol
• Couleur/Forme: Powder