TAT - GluR23Y

Ref. 3D-CRB1001142

Informations sur le produit

• Nom: TAT - GluR23Y
• Synonymes: H-YGRKKRRQRRRYKEGYNVYG-OHYGRKKRRQRRRYKEGYNVYG-acidH-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Tyr-Lys-Glu-Gly-Tyr-Asn-Val-Tyr-Gl y-OH

Description

TAT-GluR23Y is a cell penetrating peptide that inhibits phosphorylation of AMPA receptor endocytosis.Recent studies have shown that AMPA receptor endocytosis, which is a cellular mechanism underlying the formation of LTD, plays a critical role in facilitating initial extinction of learned fear. Tat-Glur23Y can block regulated AMPA and thereby prevents long-term depression (LTD) in structures such as the nucleus accumbens and dorsal hippocampus.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 2,632.4 g/mol