TP10

Ref. 3D-CRB1001299

Informations sur le produit

• Nom: TP10
• Synonymes: H-AGYLLGKINLKALAALAKKIL-NH2transportan 10AGYLLGKINLKALAALAKKIL-amideH-Ala-Gly-Tyr-Leu-Leu-Gly-Lys-Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala -Leu-Ala-Lys-Lys-Ile-Leu-NH2transportan 10

Description

TP10 is an amphipathic cell-penetrating peptide (CPPs) also known as transportan 10. Its formation involves the use of a lysine residue to form a chimeric linkage between a mastoparan 21-residue peptide, a wasp venon 14-residue peptide and 6-residues derived from the neuropeptide galanin. Structurally TP10 contains only positively charged amino acids along with 4 lysines and an N-terminus. Therefore it will produce a +5 charge under conditions of a neutral pH. It has been found that TP10 may aid molecules in penetrating through the cell membrane barrier through directly interacting with the lipid bilayer. During these interactions with the membrane TP10 will form an amphipathic alpha-helix. TP10 can be used in transduction methods.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 2,180.4 g/mol