AYPGFK Protease-Activated Receptor-4 (PAR-4)

Ref. 3D-CRB1001374

Informations sur le produit

• Nom: AYPGFK Protease-Activated Receptor-4 (PAR-4)
• Synonymes: H-AYPGKF-NH2

Description

Protease activated receptors (PARs) are a distinctive four-member family of seven transmembrane G protein-coupled receptors (GPCRs) widely expressed in inflammatory cells. PARs are cleaved by certain serine proteases to expose a tethered ligand domain, this ligand domain then binds to and activates the receptors to initiate multiple signalling cascades. These PAR-activating proteases therefore represent PAR agonists. This PAR-4 agonist peptide represents the N-terminal sequence of the 'tethered ligand' and is therefore capable of activating the receptor independently of N-terminal proteolysis.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 680.4 g/mol