Leuprolide Acetate

Ref. 3D-CRB1001489

Informations sur le produit

• Nom: Leuprolide Acetate
• Synonymes: [Pyr]-HWSY-[D-Leu]-LRP-NHEt[Pyr]-His-Trp-Ser-Tyr-[D-Leu]-Leu-Arg-Pro-NHEtLeuprolideLeuprorelin[Des-Gly10DLeu6Pro9] LH-RHEthyl Amide

Description

Leuprolide acetate is a synthetic peptide analogue of naturally occurring gonadotropin releasing hormone (GnRH also known as luteinising hormone-releasing hormone, LHRH). Leuprolide Acetate has a longer half-life and a higher affinity to the pituitary GnRH-receptor than physiological GnRH due to the presence of a D-amino acid. Leuprolide acts as a super-agonist of the pituitary gonadotropin-releasing hormone (GnRH) receptor in the hypothalamo-pituitary-gonadal axis and disrupts the maintenance of the normal hypothalamo-pituitary-gonadal axis and desensitizes the GnRH receptor. This results in lower levels of testosterone in the blood. Leuprolide is used to treat prostate cancer, endometriosis, fibroids and precocious puberty. Peptide is for research purposes only, strictly not for human use.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 1,208.6 g/mol