M12 muscle-homing peptide

Ref. 3D-CRB1001635

Informations sur le produit

• Nom: M12 muscle-homing peptide
• Synonymes: H-RRQPPRSISSHP-OH

Description

Gene therapy is potentially an ideal treatment for muscle tissue myopathies but targeting remains an issue. The large volume of muscle in the body versus the requirement for tissue-specificity is of particular concern. This heptapeptide has been shown to preferentially bind myofibers and thus can be used to study targeting of peptide/gene- delivery to muscle tissue. Research into gene therapy of Duchenne muscular dystrophy (DMD) and Spinal muscular atrophy (SMA) has been of particular interest with muscle targeting peptides.- This product has been shown to orientate to muscle and heart tissue and when conjugated to a phosphorodiamidate morpholino oligomer (PMO)-increases dystrophin expression by 25%. This product already shows ideal placement to continue cardiac research to overcome some of these issues.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 1,416.8 g/mol
• Couleur/Forme: Powder