Alpha-Casozepine

Ref. 3D-CRB1001691

Informations sur le produit

• Nom: Alpha-Casozepine
• Synonymes: H-YLGYLEQLLR-OH

Description

Alpha-Casozepine (alpha-CZP) is a tryptic hydrolysate of bovine milk alphas1-casein. The presence of bile salts facilitates alpha-CZP absorption through a Caco2 monolayer. alpha-CZP shows similarities to benzodiazepines with its anxiolytic-like activity but lack the common side effects of habituation or sedation. alpha-CZP binds to the GABAA receptor at the benzodiazepine site. alpha-CZP binds with a significantly lower affinity than benzodiazepines.Intraperitoneal administration of Alpha-Casozepine (alpha-CZP) to rodents results in anticonvulsant and sleep-protecting effects. Human administration reduces physiological stress symptoms in stressed and control patients. alpha-CZP modulated neuronal activity in brain regions linked to anxiety regulation in mice.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 1,266.7 g/mol