SARS-CoV-2 NSP7 (6-20)

Ref. 3D-CRB1001764

Informations sur le produit

• Nom: SARS-CoV-2 NSP7 (6-20)
• Synonymes: H-VKCTSVVLLSVLQQL-OH

Description

SARS-CoV-2 NSP7 is part of the RNA-dependent RNA polymerase heterotetramer for mediating coronavirus RNA synthesis. NSP7 and NSP8 form a channel to confer processivity on RNA polymerase. In addition, NSP7 aids in stabilising NSP12 regions involved in RNA binding and is essential for a highly active NSP12 polymerase complex. These factors make NSP7 a good target for developing new antiviral drugs. In addition, the identification of epitopes within the NSP7 sequence can help design more effective SARS-CoV-2 vaccines.Models have predicted epitopes exhibiting antigenicity, stability and interactions with MHC class-I and class-II molecules. NSP7 (6-20) is an epitope candidate with various HLA restrictions. This epitope can be used to better vaccine design for more durable CD4+ and CD8+ T cell responses for long-lasting immunity.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 1,629 g/mol