5-Bromo-8-fluoroquinoline-7-boronic acid
CAS : 2377606-20-5
Ref. 3D-CVD60620
| 1g | À demander | ||
| 500mg | À demander |
Informations sur le produit
5-Bromo-8-fluoroquinoline-7-boronic acid is a nucleotide analogue that has been used as a sequencing probe to study the nucleic acids of E. coli and other bacteria. 5-Bromo-8-fluoroquinoline-7-boronic acid is an analog of guanosine, which binds to RNA polymerase, preventing transcription and replication. The high frequency of human activity has been shown using a patch clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. 5-Bromo-8-fluoroquinoline boronic acid also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX
Propriétés chimiques
Question d’ordre technique sur : 3D-CVD60620 5-Bromo-8-fluoroquinoline-7-boronic acid
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