Informations sur le produit
- 2,4,5-Pyrimidinetriamine
- 2,4,5-Triaminopyrimidine
- 2,5,6-Triaminopyrimidine
- NSC 65987
- Pyrimidine, 2,4,5-triamino-
Pyrimidine-2,4,5-triamine is a nucleotide derivative that is used to study the effects of extracellular Ca2+ on cell growth. It has anticancer activity and is used in the treatment of human immunodeficiency virus (HIV) infection and other inflammatory diseases. Pyrimidine-2,4,5-triamine has been shown to inhibit phosphatases, including malonic acid phosphatase and nitro phosphatase. This inhibition leads to an accumulation of malonic acid and nitro compounds which are cytotoxic. The drug also inhibits the production of hydrogen peroxide by inhibiting surface methodology enzymes such as peroxidase or catalase. Pyrimidine-2,4,5-triamine has been shown to be resistant to hydrolysis by hydrophobic effect enzymes such as esterases or glucuronidases. The drug also causes irreversible inhibition of DNA gyrase and topoisomerase
Propriétés chimiques
Question d’ordre technique sur : 3D-DAA54650 pyrimidine-2,4,5-triamine
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