Asimadoline

CAS : 153205-46-0

Ref. 3D-DGA20546

Informations sur le produit

• Nom: Asimadoline
• Synonymes: Asimadoline [INN], Benzeneacetamide, N-((1S)-2-((3S)-3-hydroxy-1-pyrrolidinyl)-1-phenylethyl)-N-methyl-alpha-phenyl-, Benzeneacetamide, N-(2-(3-hydroxy-1-pyrrolidinyl)-1-phenylethyl)-N-methyl-alpha-phenyl-, (S-(R*,R*))-, Benzeneacetamide, N-[(1S)-2-[(3S)-3-hydroxy-1-pyrrolidinyl]-1-phenylethyl]-N-methyl-α-phenyl-, Benzeneacetamide, N-[2-(3-hydroxy-1-pyrrolidinyl)-1-phenylethyl]-N-methyl-α-phenyl-, [S-(R*,R*)]-, Emd 61753, N-((alpha S)-alpha-((3S)-3-Hydroxy-1-pyrrolidinyl)methyl)benzyl)-N-methyl-2,2-diphenylacetamide, N-((alphaS)-alpha-(((3S)-3-Hydroxy-1-pyrrolidinyl)methyl)benzyl)-N-methyl-2,2-diphenylacetamide, N-[(1S)-2-[(3S)-3-Hydroxy-1-pyrrolidinyl]-1-phenylethyl]-N-methyl-α-phenylbenzeneacetamide, N-{(1S)-2-[(3S)-3-hydroxypyrrolidin-1-yl]-1-phenylethyl}-N-methyl-2,2-diphenylacetamide, Unii-D0Vk52Nv5M

Description

Asimadoline is a compound that has been shown to have analgesic and anti-inflammatory effects. It binds to κ-opioid receptors, which are found in the central nervous system and gastrointestinal tract. Asimadoline also binds to kappa-opioid receptors, which are located on immune cells in the brain and spinal cord. This drug has been shown to inhibit the production of pro-inflammatory cytokines, such as TNF-α and IL-1β, which may be due to activation of κ-opioid receptors. Asimadoline has also been shown to inhibit Pgp substrate activity, which may explain its ability to treat bowel disease, primary sclerosing cholangitis (PSC), inflammatory bowel disease (IBD), diabetic neuropathy, and antinociceptive disorders.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 414.54 g/mol
• Formule: C₂₇H₃₀N₂O₂
• Degré de pureté: Min. 95%