Karenitecin

CAS : 203923-89-1

Ref. 3D-DIA92389

Informations sur le produit

• Nom: Karenitecin
• Synonymes: (4S)-4-Ethyl-4-hydroxy-11-(2-trimethylsilyl)ethyl)-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

Description

Karenitecin is a diagnostic agent with minimal toxicity. It is used to detect granulosa cells in human serum and is also an immunohistochemical marker for the diagnosis of gliomas. Karenitecin binds to α1-acid glycoprotein, which is found at high levels in plasma and cerebrospinal fluid, and has been shown to have potent antitumor activity. The drug can be administered intravenously or intra-arterially, with a low risk of toxicity. Karenitecin has been shown to have antineoplastic properties by inhibiting mitochondrial membrane potential, which may be due to its ability to bind to the a-ring of ATP synthase.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 448.6 g/mol
• Formule: C₂₅H₂₈N₂O₄Si
• Degré de pureté: Min. 95%