N-Cyclopropyl-1H-indole-4-carboxamide
CAS : 1153845-91-0
Ref. 3D-DWB84591
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Informations sur le produit
N-Cyclopropyl-1H-indole-4-carboxamide (CPI) is a pyrimidine analog that has been shown to have the ability to inhibit cell growth and induce apoptosis in cancer cells. It has also been shown to have anti-inflammatory effects in animal models of bowel disease, and is being investigated for its potential use in treating inflammatory bowel diseases such as Crohn's disease. CPI has also been shown to be effective against cancer cells, with some studies showing it can inhibit colon cancer tumor growth by up to 50% when administered orally.
CPI was originally synthesized from a 1H-indole derivative, which was then modified by adding a cyclopropyl group and an amide substituent. The compound’s activity against cancer cells can be attributed to its ability to induce apoptosis by inhibiting protein synthesis.