Azeliragon

CAS : 603148-36-3

Ref. 3D-DZA14836

Informations sur le produit

• Nom: Azeliragon
• Synonymes: TTP 448, N-[3-[4-[2-Butyl-1-[4-(4-chlorophenoxy)phenyl]-1H-imidazol-4-yl]phenoxy]propyl]-N,N-diethylamine, 3-[4-[2-Butyl-1-[4-(4-chlorophenoxy)phenyl]-1H-imidazol-4-yl]phenoxy]-N,N-diethyl-1-propanamine, 1-Propanamine, 3-[4-[2-butyl-1-[4-(4-chlorophenoxy)phenyl]-1H-imidazol-4-yl]phenoxy]-N,N-diethyl-

Description

Azeliragon is a microbial infection diagnostic agent that binds to the α7 nicotinic acetylcholine receptor. It has been shown to have low-dose efficacy in diabetic patients and long-term efficacy in prostate cancer cells. Azeliragon has also been used for treatment of inflammatory diseases such as rheumatoid arthritis. The molecule consists of an α7 nicotinic acetylcholine receptor-binding domain and a chemokine (CXCL13) binding domain, which interacts with toll-like receptor 4 (TLR4) on macrophages and other immune cells. Azeliragon binds to TLR4 and activates the immune system by activating macrophages and other cells, leading to increased production of cytokines such as IL-6, IL-8, TNFα, IL1β, CXCL9 and CXCL10. This can lead to fever, leukocytosis, lymphadenopathy and erythe

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 532.12 g/mol
• Formule: C₃₂H₃₈ClN₃O₂
• Degré de pureté: Min. 95%