Mps1-IN-2

CAS : 1228817-38-6

Ref. 3D-DZB81738

Informations sur le produit

• Nom: Mps1-IN-2
• CAS: 1228817-38-6

Description

Mps1-IN-2 is a potent and selective inhibitor of the mitotic kinase Mps1. It binds to the ATP-binding site of Mps1 and inhibits its activity, leading to cell death by apoptosis or necrosis. Mps1-IN-2 has shown anti-tumor activity against cancer cells in vitro and in vivo without any significant side effects, making it an attractive candidate for cancer therapy. The crystal structure of Mps1-IN-2 bound to the kinase domain revealed that it binds to a pocket with high affinity, where ATP binding leads to conformational changes that affect the other domains of the enzyme. This study has also shown that Mps1-IN-2 inhibits spindle formation and cellular proliferation in cancer cells.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 480.6 g/mol
• Formule: C₂₆H₃₆N₆O₃
• Degré de pureté: Min. 95%