Norcantharidin

CAS : 29745-04-8

Ref. 3D-EBA74504

Informations sur le produit

• Nom: Norcantharidin
• Synonymes: (3aR,4S,7R,7aS)-hexahydro-4,7-epoxy-2-benzofuran-1,3-dione, (3aR,4S,7R,7aS)-rel-Hexahydro-4,7-epoxyisobenzofuran-1,3-dione, 4,10-Dioxatricyclo[5.2.1.0(2,6)]decane-3,5-dione, 4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-, (3aR,4S,7R,7aS)-rel-, 4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-, (3aα,4β,7β,7aα)-, 7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic Anhydride, 7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic anhydride, exo-, 7-Oxabicyclo[2.2.1]heptane-exo-cis-2,3-dicarboxylic anhydride, Demehylcantharidin, Demethylcantharidin, Exo-7-Oxabicyclo[2.2.1]Heptane-2,3-Dicarboxylic Anhydride, Hexahydro-4,7-Epoxy-2-Benzofuran-1,3-Dione, Isocantharidin, NSC 59023, exo-7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid anhydride, rel-(3aR,4S,7R,7aS)-Hexahydro-4,7-epoxyisobenzofuran-1,3-dione
• CAS: 29745-04-8

Description

Norcantharidin is an antitumor drug that belongs to the group of pyrazole derivatives. It has shown significant cytotoxicity against human cancer cells in vitro and in vivo. Norcantharidin induces apoptosis by binding to DNA, inhibiting RNA polymerase activity, and blocking the synthesis of proteins needed for cell division. Norcantharidin also inhibits growth of the tumor by inducing differentiation of epithelial mesenchymal cells into fibroblasts. This drug has been shown to induce apoptosis in hl-60 cells at low doses (10 µM) and has a significant cytotoxicity against HL-60 cells at high doses (>10 µM).

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 168.15 g/mol
• Formule: C₈H₈O₄
• Degré de pureté: Min. 95%