Informations sur le produit
- Dofequidar [INN]
- 1-(Diphenylacetyl)-4-((2RS)-2-hydroxy-3-(5-quinolyloxy)propyl)piperazine
- Unii-0Bjk6B565B
- 1-{4-[2-Hydroxy-3-(Quinolin-5-Yloxy)Propyl]Piperazin-1-Yl}-2,2-Diphenylethanone
Dofequidar is a pyrimidine compound that is used as an immunosuppressant drug. It is used to treat autoimmune diseases and inflammatory bowel disease. Dofequidar has been shown to inhibit the transcription-polymerase chain reaction (PCR) of T lymphocytes in vitro, which may be due to its ability to bind hydrogen bonds in DNA. Dofequidar also binds to monoclonal antibodies, including anti-CD3 and anti-CD20, and inhibits the proliferation of mouse hippocampal cells.