Dipeptidyl-Peptidase IV, human, recombinant

Ref. 3D-ENZ-375

Informations sur le produit

• Nom: Dipeptidyl-Peptidase IV, human, recombinant
• Synonymes: CD26, ADABP, ADCP2, DPPIV, TP103, DPP4, Dipeptidyl peptidase 4, Dipeptidyl peptidase IV, DPP IV, T-cell activation antigen CD26, Ade nosine deaminase complexing protein 2
• Marque: Biosynth
• Description: Dipeptidyl-peptidase IV (DPP4) is a complex enzyme that is expressed in the pancreas and regulates glucose-dependent insulinotropic polypeptides. DPP4 cleaves the amino terminal dipeptide from these polypeptides, which prevents the activation of pancreatic β-cells. The recombinant human form of this enzyme has been shown to activate T cells and induce apoptosis in insect cells. Its activity against chemokines in vitro may be due to its ability to cleave glycosylated polypeptides. This enzyme also has anti-inflammatory effects by inhibiting the production of proinflammatory cytokines such as tumor necrosis factor α (TNFα), interleukin 1β (IL1β), and IL6.

Propriétés chimiques

• Degré de pureté: Min. 95%