N-Desmethyl imatinib mesylate

CAS : 404844-03-7

Ref. 3D-ERA84403

Informations sur le produit

• Nom: N-Desmethyl imatinib mesylate
• Synonymes: Benzamide, N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-4-(1-piperazinylmethyl)-, monomethanesulfonate, CGP 74588, Benzamide, N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-4-(1-piperazinylmethyl)-, methanesulfonate (1:1)

Description

N-Desmethyl imatinib mesylate is an active metabolite of Imatinib Mesylate, a drug used to treat metastatic colorectal cancer. The compound is an inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR) and is taken orally. N-Desmethyl imatinib mesylate has been shown to be effective in women with metastatic colorectal cancer, producing a hematologic response in 67% of patients. This compound has also been found to have a longer half-life than Imatinib Mesylate and may be used as a substitute for this drug in women with metastatic colorectal cancer who are unable to take oral medications.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 575.7 g/mol
• Formule: C₂₉H₃₃N₇O₄S
• Degré de pureté: Min. 95%