2-Amino-5-bromo-3-iodopyridine

CAS : 381233-96-1

Ref. 3D-FA09641

Informations sur le produit

• Nom: 2-Amino-5-bromo-3-iodopyridine
• Synonymes: 5-Bromo-3-iodopyridin-2-amine, 5-Bromo-3-iodo-2-aminopyridine

Description

2-Amino-5-bromo-3-iodopyridine (2AB3IP) is a cacchi anthelmintic that is active against the trophozoites of Giardia lamblia. 2AB3IP also has antimicrobial properties, but is not active against bacteria. The high lipophilicity and pharmacokinetic properties of this drug make it a potential therapeutic candidate for the treatment of giardiasis. The mechanism of action of 2AB3IP is mediated by potassium t-butoxide, which activates the drug to form its reactive intermediate. This intermediate reacts with DNA in the parasite to form covalent adducts. This process leads to inhibition of RNA synthesis and subsequent cell death.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 298.9 g/mol
• Formule: C₅H₄BrIN₂
• Degré de pureté: Min. 95%
• Couleur/Forme: White to tan solid.