Acetyl-(Ala11·15)-Endothelin-1 (6-21)

CAS : 143113-45-5

Ref. 3D-FA110316

Informations sur le produit

• Nom: Acetyl-(Ala11·15)-Endothelin-1 (6-21)
• Synonymes: Ac-Leu-Met-Asp-Lys-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp-OH Ac-LMDKEAVYFAHLDIIW-OH
• Marque: Biosynth
• Description: Acetyl-(Ala11·15)-Endothelin-1 (6-21) Ac-Leu-Met-Asp-Lys-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-IleTrpOH is a recombinant peptide that is a potent endothelin receptor antagonist. It binds to the endothelin receptor, blocking the binding of endothelin and preventing activation of the receptor. Acetyl-(Ala11·15)-Endothelin (6–21) Ac has been shown to inhibit atrial natriuretic peptide levels and reduce blood pressure in experimental models. This drug also prevents balloon injury by blocking the binding of endothelin to its receptors and inhibits growth factor β1, which is an important mediator in pulmonary hypertension. The mechanism of action for this drug is not fully understood, but it may work through inhibiting

Propriétés chimiques

• Masse moléculaire: 2,006.32 g/mol
• Formule: C₉₆H₁₄₀N₂₀O₂₅S
• Degré de pureté: Min. 95%