Ac-Ile-Glu-Thr-Asp-AMC

CAS : 348079-17-4

Ref. 3D-FA110583

Informations sur le produit

• Nom: Ac-Ile-Glu-Thr-Asp-AMC
• Synonymes: Ac-IETD-AMC, Caspase-3 Precursor Protease Substrates

Description

Ac-Ile-Glu-Thr-Asp-AMC is a reactive, nonsteroidal anti-inflammatory drug that inhibits the activity of survivin, which is an important protein for the survival of prostate cancer cells. Ac-Ile-Glu-Thr-Asp-AMC also inhibits mitochondrial membrane potential in prostate cancer cells and normal peripheral blood mononuclear cells, leading to apoptosis. The biochemical properties of Ac-Ile-Glu-Thr-Asp-AMC are similar to those of other NSAIDs. This drug has been shown to inhibit protein synthesis in experimental models and hydrochloric acid causes mitochondrial membrane depolarization, which triggers apoptosis.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 675.68 g/mol
• Formule: C₃₁H₄₁N₅O₁₂
• Degré de pureté: Min. 95 Area-%
• Couleur/Forme: Powder