Z-Asp-Glu-Val-Asp-chloromethylketone

CAS : 250584-13-5

Ref. 3D-FA111069

Informations sur le produit

• Nom: Z-Asp-Glu-Val-Asp-chloromethylketone
• Synonymes: Z-DEVD-CMK
• Marque: Biosynth
• Description: Z-Asp-Glu-Val-Asp-chloromethylketone is a reactive compound that inhibits the activity of proteases and induces neuronal death. Z-Asp-Glu-Val-Asp-chloromethylketone has been shown to induce necrotic cell death in malignant brain cells and has neurotrophic properties. It also causes mitochondrial membrane depolarization, which leads to mitochondrial cytochrome c release and subsequent apoptosis. The reaction mechanism is still unclear but it may involve hydrogen bonding between the ketone group and the amide nitrogen atom of the aspartate residue.

Propriétés chimiques

• Masse moléculaire: 643.04 g/mol
• Formule: C₂₇H₃₅ClN₄O₁₂
• Degré de pureté: Min. 95%