AMD 3100 octahydrochloride

CAS : 155148-31-5

Ref. 3D-FA148913

Informations sur le produit

• Nom: AMD 3100 octahydrochloride
• Synonymes: 1,1'-(Benzene-1,4-Diyldimethanediyl)Bis-1,4,8,11-Tetraazacyclotetradecane Octahydrochloride Dihydrate, 1,1′-[1,4-Phenylenebis(methylene)]bis[1,4,8,11-tetraazacyclotetradecane] hydrochloride (1:8), 1,4,8,11-Tetraazacyclotetradecane, 1,1′-[1,4-phenylenebis(methylene)]bis-, hydrochloride (1:8), 1,4,8,11-Tetraazacyclotetradecane, 1,1′-[1,4-phenylenebis(methylene)]bis-, octahydrochloride, Amd 3100, Jm 3100, Plerixafore 8HCl, Sid 791

Description

Antagonises CXCR4 selectively by blocking Ca2+ release (IC50 from 0.02 to 0.13 µM). Studied in SDF-1/CFXCR4-dependent functions in HIV, rheumatoid arthritis and breast cancer metastasis. Enhances mobilization of hematopoietic stem cells (HSCs) and Hematopoietic progenitor cells (HPCs) for re-populating hematopoietic progenitors for transplants in vivo and attenuates cocaine-induced locomotor activation.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 794.47 g/mol
• Formule: C₂₈H₆₂Cl₈N₈
• Degré de pureté: Min. 98 Area-%
• Couleur/Forme: Powder