2-Amino-3-(4-hydroxy-3-methoxyphenyl)propanoic acid

CAS : 7636-26-2

Ref. 3D-FA153636

Informations sur le produit

• Nom: 2-Amino-3-(4-hydroxy-3-methoxyphenyl)propanoic acid
• Synonymes: 3-(4-Hydroxy-3-methoxyphenyl)alanine, 3-Methoxy-4-hydroxyphenylalanine, 3-Methoxy-<span class="text-smallcaps">D</span>,L-tyrosine, 3-Methoxy-dl-tyrosine, 3-Methoxytyrosine, 4-Hydroxy-3-methoxyphenylalanine, <span class="text-smallcaps">DL</span>-3-Methoxy-4-hydroxyphenylalanine, <span class="text-smallcaps">DL</span>-3-Methoxytyrosine, <span class="text-smallcaps">DL</span>-3-O-Methyldopa, Alanine, 3-(4-hydroxy-3-methoxyphenyl)-, Alanine,3-(4-hydroxy-3-methoxyphenyl)- (8CI), DL-3-Methoxy-4-hydroxyphenylalanine, DL-3-Methoxytyrosine, DL-3-O-Methyldopa, Nsc 122476
• CAS: 7636-26-2

Description

2-Amino-3-(4-hydroxy-3-methoxyphenyl)propanoic acid is a metabolite of levodopa in the body. It is formed by oxidation of levodopa via the enzyme catechol-O-methyltransferase (COMT). This compound is used as an analytical reagent to measure levels of levodopa and its metabolites in biological samples. 2-Amino-3-(4-hydroxy-3-methoxyphenyl)propanoic acid can also be used to diagnose Parkinson’s disease, since it is produced in excess when dopamine production decreases due to the degeneration of dopaminergic neurons. The concentration-time curve for this compound can be used to calculate the clearance rate of levodopa from the blood plasma.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 211.21 g/mol
• Formule: C₁₀H₁₃NO₄
• Degré de pureté: Min. 95 Area-%
• Couleur/Forme: Powder
• InChI: InChI=1S/C10H13NO4/c1-15-9-5-6(2-3-8(9)12)4-7(11)10(13)14/h2-3,5,7,12H,4,11H2,1H3,(H,13,14)
• Code InChI: InChIKey=PFDUUKDQEHURQC-UHFFFAOYSA-N
• SMILES: COc1cc(CC(N)C(=O)O)ccc1O