Informations sur le produit
Nom :
Adaphostin
Synonymes :
- 4-[[(2,5-Dihydroxyphenyl)methyl]amino]benzoic acid tricyclo[3.3.1.13,7]dec-1-yl esterNSC 680410
- Nsc-680410
- Tricyclo[3.3.1.1~3,7~]Dec-1-Yl 4-[(2,5-Dihydroxybenzyl)Amino]Benzoate
Description :
Adaphostin is a potential anticancer agent that has been shown to inhibit oxidative injury and induce apoptosis in k562 cells. It also inhibits the production of reactive oxygen species and alters iron homeostasis. Adaphostin has been shown to inhibit mitochondrial membrane potential, dna binding activity, enzyme activities, and cell proliferation in vitro. This drug also has synergistic effects with other anticancer drugs such as doxorubicin. Adaphostin has been found to be active against various carcinoma cell lines and resistant mutants of these cells. The structural analysis of adaphostin revealed that it is a novel compound with an aminothiazole core and a pyridine ring system with two heterocycles attached at the 3-position.
Avis:
Nos produits sont destinés uniquement à un usage en laboratoire. Pour tout autre usage, veuillez nous contacter.
Marque:
Biosynth
Stockage à long terme :
Notes :
Propriétés chimiques
Masse moléculaire :
393.48 g/mol
Formule :
C24H27NO4
Degré de pureté :
Min. 95%
MDL:
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Merck :
Code SH :
