R-(+)-Aminoglutethimide L-tartrate

CAS : 57344-88-4

Ref. 3D-FA17756

Informations sur le produit

• Nom: R-(+)-Aminoglutethimide L-tartrate
• Synonymes: R-(+)-3-(4-Aminophenyl)-3-ethyl-2,6-piperidinedione L-tartrate saltd-Aminoglutethimide L-tartrate
• Marque: Biosynth
• Description: R-(+)-Aminoglutethimide is a potent inhibitor of mitochondrial electron transport and the cleavage enzyme 4-phenylimidazole. It inhibits mitochondrial ATP production by binding to the inner mitochondrial membrane and preventing the passage of electrons from cytochrome c oxidase to oxygen. This drug has been shown to be effective in treating corticotroph adenoma, a benign tumor of the anterior pituitary gland, which is due to excessive secretion of ACTH by the gland. R-(+)-Aminoglutethimide can also be used for treatment of Cushing's syndrome due to its ability to inhibit cortisol synthesis in the adrenal cortex. This drug has been shown to act as a potent inhibitor of progesterone synthesis in bovine and human ovaries, leading to decreased levels of pregnenolone, which is an important precursor for other steroid hormones such as testosterone or estrogens.

Propriétés chimiques

• Masse moléculaire: 382.37 g/mol
• Formule: C₁₇H₂₂N₂O₈
• Degré de pureté: Min. 95%
• Couleur/Forme: White To Off-White Solid
• InChI: InChI=1S/C13H16N2O2.C4H6O6/c1-2-13(8-7-11(16)15-12(13)17)9-3-5-10(14)6-4-9;5-1(3(7)8)2(6)4(9)10/h3-6H,2,7-8,14H2,1H3,(H,15,16,17);1-2,5-6H,(H,7,8)(H,9,10)
• Code InChI: InChIKey=DQUXPVVSVXIQNE-UHFFFAOYSA-N
• SMILES: CCC1(c2ccc(N)cc2)CCC(=O)NC1=O.O=C(O)C(O)C(O)C(=O)O