Informations sur le produit
- 5-Amino-2-[2-(dimethylamino)ethyl]-1H-benz[de]isoquinoline-1,3(2H)-dioneFA 142M-FA 142
- 1H-Benz[de]isoquinoline-1,3(2H)-dione, 5-amino-2-[2-(dimethylamino)ethyl]-
- 5-Amino-2-[2-(dimethylamino)ethyl]-1H-benz[de]isoquinoline-1,3(2H)-dione
- 5-amino-2-[2-(dimethylamino)ethyl]-1H-benzo[de]isoquinoline-1,3(2H)-dione
- Benzisoquinolinedione
- Fa 142
- M-Fa 142
- Made-Fa 142
- NSC 308847
- Nafidimide
- Voir d'autres synonymes
- Nci 308847
Amonafide is a basic fibroblast growth factor (bFGF) cyclic peptide that has been shown to inhibit the proliferation of renal cell cancer cells. It also has anti-cancer properties, including inhibiting the viability of cancer cells and preventing angiogenesis. Amonafide inhibits the mitochondrial membrane potential of both normal and cancer cells, which leads to a decrease in ATP synthesis. Amonafide is chemically stable at high temperatures, making it an ideal candidate for use in hyperproliferative diseases such as cancer.