Artemisitene

CAS : 101020-89-7

Ref. 3D-FA17993

Informations sur le produit

• Nom: Artemisitene
• Synonymes: (3R,5aS,6R,8aS,12S,12aR)-Octahydro-3,6-dimethyl-9-methylene-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one(+)-Artemisite neDehydroqinghaosu, 3,12-Epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin-10(3H)-one, octahydro-3,6-dimethyl-9-methylene-, (3R-(3alpha,5abeta,6beta,8abeta,12beta,12aR*))-, (3R,5aS,6R,12S,12aR)-3,6-dimethyl-9-methylideneoctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one
• CAS: 101020-89-7

Description

Artemisitene is a sesquiterpene lactone that has been used as an anti-infective agent. It has shown cytotoxic activity against human lung cells, and also inhibits the growth of human cervical cancer cells in tissue culture. Artemisitene is metabolized to artemisinin, which is the active form that binds to DNA and blocks cellular replication. Artemisitene's cytotoxic activity is due to its ability to inhibit the synthesis of DNA, RNA, and proteins by binding to ribosomes. Artemisitene can be administered orally or intravenously and shows good bioavailability following oral administration.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 280.32 g/mol
• Formule: C₁₅H₂₀O₅
• Degré de pureté: Min. 95%
• Couleur/Forme: Powder