trans-4-Aminoadamantan-1-ol

CAS : 62058-03-1

Ref. 3D-FA31143

Informations sur le produit

• Nom: trans-4-Aminoadamantan-1-ol
• Synonymes: (1R,3S,4S,5S,7S)-Rel-4-aminoadamantan-1-ol, Trans-4-Amino-1-hydroxy-adamantane, Tricyclo[3.3.1.13,7]decan-1-ol,4-amino-,(1α,3α,4α,5β,7α)-

Description

Trans-4-aminoadamantan-1-ol is a reactive intermediate that has been shown to inhibit the activity of 11β-hydroxysteroid dehydrogenase (11βHSD) and its cofactor NADP in vitro. This inhibition leads to an increase in glucocorticoids, which are potent anti-inflammatory agents. Trans-4-aminoadamantan-1-ol can be used as a lead compound for the development of novel drugs for the treatment of autoimmune diseases. Trans-4-aminoadamantan-1-ol has also shown inhibitory activities against cytokine receptors with IC50 values ranging from 0.2 to 13 μM.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 167.25 g/mol
• Formule: C₁₀H₁₇NO
• Degré de pureté: Min. 95%