3-Acetamidophthalic anhydride

CAS : 6296-53-3

Ref. 3D-FA63286

Informations sur le produit

• Nom: 3-Acetamidophthalic anhydride
• Synonymes: acetamide, N-(1,3-dihydro-1,3-dioxo-4-isobenzofuranyl)-, 1,3-Dioxo-2-isoindolineacetic acid

Description

3-Acetamidophthalic anhydride is a potent, selective and efficient reagent for the synthesis of 3-substituted amines. This compound is prepared by reacting an acetamide with phthalic anhydride in the presence of an alkali metal hydroxide. The reaction yields are in excess of 99%. The chemical transformation can be carried out on either aliphatic or aromatic amines. 3-Acetamidophthalic anhydride has been used to synthesize apremilast, a drug that has potent activity against TNF-α.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 205.17 g/mol
• Formule: C₁₀H₇NO₄
• Degré de pureté: Min. 95%
• Couleur/Forme: Off-White Powder
• InChI: InChI=1S/C10H7NO4/c1-5(12)11-7-4-2-3-6-8(7)10(14)15-9(6)13/h2-4H,1H3,(H,11,12)
• Code InChI: InChIKey=PAUAJOABXCGLCN-UHFFFAOYSA-N
• SMILES: CC(=O)Nc1cccc2c1C(=O)OC2=O