Informations sur le produit
- Cyclopentanecarboxylic acid, 1-methyl-2-oxo-, ethyl ester
- Ethyl 1-methyl-2-oxocyclopentanecarboxylate
Ethyl 1-methyl-2-oxocyclopentane-1-carboxylate is a cyclopentenone that has been shown to be effective against epidermoid carcinoma cells and lymphocytic leukemia. It has antitumor activity in vivo, with a good cytotoxicity profile. This compound binds to the DNA of tumor cells, causing mismatched base pairing through its diastereomeric interactions. This binding leads to disruption of the DNA helix, which causes cell death by apoptosis. Ethyl 1-methyl-2-oxocyclopentane-1-carboxylate also inhibits the growth of tissue culture cells. The toxic effects on these cells are dose dependent and can be reduced by irradiation or ethylene gas treatment.
Propriétés chimiques
Question d’ordre technique sur : 3D-FAA45388 ethyl 1-methyl-2-oxocyclopentane-1-carboxylate
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