Informations sur le produit
- 1-Indanone, 5-bromo-
- 1H-Inden-1-one, 5-bromo-2,3-dihydro-
- 5-Bromo-2,3-Dihydroinden-1-One
- 5-Bromo-2,3-indan-1-one
- 5-Bromoindan-1-one
- 5-Bromoindanon
- 5-Bromoindanone
- 5-bromo-2,3-dihydro-1H-inden-1-one
5-Bromo-1-indanone is a synthetic compound that belongs to the group of palladium complexes. It has been shown to inhibit the activity of b-raf, which is a protein kinase that plays an important role in signal transduction pathways related to cell proliferation and differentiation. 5-Bromo-1-indanone also has potent antagonistic effects on other proteins that are involved in these pathways, including c-KIT, c-MET, and PDGFRα. This drug has minimal biological properties in vitro and shows no activity against human cancer cells lacking dopamine D3 receptor. 5-Bromo-1-indanone does not show any affinity for the nod-like receptor or for any of its known subtypes, but it does inhibit hydroxamic acid synthase enzymes with high potency. This compound is used as a starting material for the synthesis of hydroxamic acids with potential therapeutic application as selective dopamine D3 antagonists.
