4'-Bromo-2,2,2-trifluoroacetophenone

CAS : 16184-89-7

Ref. 3D-FB105944

Informations sur le produit

• Nom: 4'-Bromo-2,2,2-trifluoroacetophenone
• Synonymes: 1-(4-Bromophenyl)-2,2,2-trifluoroethan-1-one, 1-(4-Bromophenyl)-2,2,2-trifluoroethanone, 2,2,2-Trifluoro-1-(4-bromophenyl)ethanone, 4-Bromo-α,α,α-trifluoroacetophenone, 4-Bromophenyl trifluoromethyl ketone, 4-Bromotrifluoroacetone, Acetophenone, 4′-bromo-2,2,2-trifluoro-, Ethanone, 1-(4-bromophenyl)-2,2,2-trifluoro-, p-Bromo-α,α,α-trifluoroacetophenone, p-Bromophenyl trifluoromethyl ketone, p-Bromotrifluoroacetophenone

Description

4'-Bromo-2,2,2-trifluoroacetophenone is a pesticide that has been shown to have cardiac effects. It blocks the passage of calcium ions into the heart cells by inhibiting the opening of voltage-gated calcium channels in the cell membrane. This action causes an increase in blood pressure and a decrease in cardiac contractility. 4'-Bromo-2,2,2-trifluoroacetophenone also inhibits mitochondrial cytochrome oxidase and prevents cellular respiration. The concentration-response curve for this compound was determined using rat myocardial tissue. Cardiac dysfunction can be treated with inotropes like dopamine to increase cardiac contractility and maintain blood pressure.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 253.02 g/mol
• Formule: C₈H₄BrF₃O
• Degré de pureté: Min. 95%
• InChI: InChI=1S/C8H4BrF3O/c9-6-3-1-5(2-4-6)7(13)8(10,11)12/h1-4H
• Code InChI: InChIKey=IHGSAQHSAGRWNI-UHFFFAOYSA-N
• SMILES: O=C(c1ccc(Br)cc1)C(F)(F)F