Boc-Val-Leu-Lys-AMC acetate salt

CAS : 73554-84-4

Ref. 3D-FB110487

Informations sur le produit

• Nom: Boc-Val-Leu-Lys-AMC acetate salt
• Synonymes: 7: PN: WO2004106541 PAGE: 15 claimed protein, <span class="text-smallcaps">L</smallcap>-Lysinamide, N-[(1,1-dimethylethoxy)carbonyl]-<smallcap>L</smallcap>-valyl-<smallcap>L</span>-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-, Boc-Val-Leu-Lys-AMC, Boc-Val-Leu-Lys-Amc Acetate, N-(tert-butoxycarbonyl)-L-valyl-L-leucyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-lysinamide, N-[(1,1-Dimethylethoxy)carbonyl]-<span class="text-smallcaps">L</smallcap>-valyl-<smallcap>L</smallcap>-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-<smallcap>L</span>-lysinamide, tert-(Butyloxycarbonyl)-<span class="text-smallcaps">L</smallcap>-valyl-<smallcap>L</smallcap>-leucyl-<smallcap>L</span>-lysine-7-amino-4-methylcoumarin
• CAS: 73554-84-4

Description

Boc-Val-Leu-Lys-AMC acetate salt is a protease inhibitor that binds to the active site of trypsin and inhibits its proteolytic activity. It has been shown to protect neuronal cells from death caused by amyloid beta (Aβ) peptide. Boc-Val-Leu-Lys-AMC acetate salt also inhibits the secretion of proinflammatory cytokines and reduces the permeability of mitochondrial membranes in human neutrophils. This drug is stable in acidic environments, with a pH optimum of 2.0, but is sensitive to alkaline conditions with a pH optimum of 8.5. Boc-Val-Leu-Lys-AMC acetate salt has been shown to bind to casein, which may result in high values on sephadex g100 chromatography.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 675.81 g/mol
• Formule: C₃₂H₄₉N₅O₇•C₂H₄O₂
• Degré de pureté: Min. 98 Area-%
• Couleur/Forme: Powder