N-(1,3-Benzodioxol-5-ylmethyl)-2-chloroacetamide

CAS : 40023-03-8

Ref. 3D-FB114058

Informations sur le produit

• Nom: N-(1,3-Benzodioxol-5-ylmethyl)-2-chloroacetamide
• Synonymes: Acetamide, N-(1,3-benzodioxol-5-ylmethyl)-2-chloro-, N-[(Benzodioxol-5-yl)methyl]-2-chloroacetamide

Description

N-(1,3-Benzodioxol-5-ylmethyl)-2-chloroacetamide (BCA) is a dithiocarbamate that has significant cytotoxic activity against human lung cancer cell lines. It inhibits the growth of cancer cells by binding to nucleophilic sites on DNA and preventing DNA synthesis. BCA also inhibits the production of reactive oxygen species in cells. This inhibition enhances cisplatin's cytotoxicity in glioma cells, which may be due to a synergistic effect between these two drugs.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 227.64 g/mol
• Formule: C₁₀H₁₀ClNO₃
• Degré de pureté: Min. 95%
• InChI: InChI=1S/C10H10ClNO3/c11-4-10(13)12-5-7-1-2-8-9(3-7)15-6-14-8/h1-3H,4-6H2,(H,12,13)
• Code InChI: InChIKey=PLXGAUGZSOPIIG-UHFFFAOYSA-N
• SMILES: O=C(CCl)NCc1ccc2c(c1)OCO2