(R)-(+)-5,5'-Bis(diphenylphosphino)-4,4'-bi-1,3-benzodioxole

CAS : 244261-66-3

Ref. 3D-FB138064

Informations sur le produit

• Nom: (R)-(+)-5,5'-Bis(diphenylphosphino)-4,4'-bi-1,3-benzodioxole
• Synonymes: (R)-Segphos, 1,1′-[(4R)-[4,4′-Bi-1,3-benzodioxole]-5,5′-diyl]bis[1,1-diphenylphosphine], Phosphine, 1,1′-[(4R)-[4,4′-bi-1,3-benzodioxole]-5,5′-diyl]bis[1,1-diphenyl-, Phosphine, [(4R)-[4,4′-bi-1,3-benzodioxole]-5,5′-diyl]bis[diphenyl-

Description

(R)-(+)-5,5'-Bis(diphenylphosphino)-4,4'-bi-1,3-benzodioxole is a chiral nitrogen nucleophile that can be used as an asymmetric catalyst in the hydrogenation of prochiral substrates. It is synthesized by a palladium-mediated reaction between 2-bromoacetophenone and diphenylphosphine oxide. The enantiomers of the product are separated by column chromatography on silica gel with hexane/dichloromethane (90:10) as eluent. The (R)-enantiomer has been shown to be more active than the (S)-enantiomer in hydrogenating racemic substrates such as propanal and cyclopentanone.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 610.57 g/mol
• Formule: C₃₈H₂₈O₄P₂
• Degré de pureté: Min. 95%