tert-Butyl sulfamoylcarbamate

CAS : 148017-28-1

Ref. 3D-FB142916

Informations sur le produit

• Nom: tert-Butyl sulfamoylcarbamate
• Synonymes: 1,1-Dimethylethyl N-(aminosulfonyl)carbamate, BOC-Sulfamide, Carbamic acid, (aminosulfonyl)-, 1,1-dimethylethyl ester, Carbamic acid, N-(aminosulfonyl)-, 1,1-dimethylethyl ester, N-(Aminosulfonyl)carbamic acid 1,1-dimethylethyl ester, Tert-Butyl Sulfamoylcarbamate, tert-Butoxycarbonylsulfamide, tert-Butyl N-(sulfamoyl)carbamate
• CAS: 148017-28-1

Description

Tert-Butyl sulfamoylcarbamate is an antibacterial agent which inhibits the growth of gram-negative bacteria by binding to the active site of β-lactamase enzymes. It has been shown to be effective against Pseudomonas aeruginosa, a common cause of hospital infections. This compound is also used as a protective agent in amines and sulfuric acid esters, such as sulfonyl chlorides. Tert-butyl sulfamoylcarbamate can be synthesized by reacting tert-butyl carbamate with chloroacetic acid in an exothermic reaction at cryogenic temperatures. The reaction can be conducted under basic conditions or in the presence of a base catalyst, such as potassium hydroxide or sodium ethoxide. Tert-Butyl sulfamoylcarbamate can be isolated by removing solvent in vacuo and recrystallizing from diethylether at reaction temperatures below 30°C.

• Marque: Biosynth

Propriétés chimiques

• Degré de pureté: Min. 95%