5-Bromo-2-methylbenzenesulfonylchloride

CAS : 69321-56-8

Ref. 3D-FB150737

Informations sur le produit

• Nom: 5-Bromo-2-methylbenzenesulfonylchloride
• Synonymes: 5-Bromo-2-methylbenzene-1-sulfonyl chloride, Benzenesulfonyl chloride, 5-bromo-2-methyl-

Description

5-Bromo-2-methylbenzenesulfonylchloride is a small molecule that inhibits the transcription factor BRD4 in tumor cells. It binds to bromodomains and prevents binding of transcription factors that regulate gene expression, leading to inhibition of tumor growth. 5-Bromo-2-methylbenzenesulfonylchloride has been shown to be orally active in mice with prostate cancer and has a high potency in cell-based assays. The stability of this agent is dependent on the presence of family members, such as P450 and glutathione reductase, which are necessary for metabolism. 5-Bromo-2-methylbenzenesulfonylchloride also displays permeability across cell membranes.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 269.54 g/mol
• Formule: C₇H₆BrClO₂S
• Degré de pureté: Min. 95%
• InChI: InChI=1S/C7H6BrClO2S/c1-5-2-3-6(8)4-7(5)12(9,10)11/h2-4H,1H3
• Code InChI: InChIKey=OYSAFEFFWRNQJF-UHFFFAOYSA-N
• SMILES: Cc1ccc(Br)cc1S(=O)(=O)Cl