8-Bromo-6-methylquinoline
CAS : 84839-95-2
Ref. 3D-FB153107
1g | À demander | ||
50mg | À demander | ||
100mg | À demander | ||
250mg | À demander | ||
500mg | À demander |
Informations sur le produit
- Quinoline, 8-Bromo-6-Methyl-
8-Bromo-6-methylquinoline is a synthetic compound that has been shown to be a potent TNFα inhibitor. The pharmacological activity of 8-Bromo-6-methylquinoline was tested in vitro and found to inhibit the production of TNFα from LPS-stimulated mouse peritoneal macrophages, which may be due to its ability to bind the terminal alkynes on the TNFα receptor. Optimization studies were conducted on 8-Bromo-6-methylquinoline, which led to an increased yield of the desired product. This ligand also has a high affinity for chloride ions and can form coordination geometry with them. The binding affinity of 8-Bromo-6-methylquinoline for TNFα has been evaluated using molecular dynamics simulations and was found to have an interaction profile similar to that of other TNFα inhibitors.
Propriétés chimiques
Question d’ordre technique sur : 3D-FB153107 8-Bromo-6-methylquinoline
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