Beauvericin

CAS : 26048-05-5

Ref. 3D-FB18149

Informations sur le produit

• Nom: Beauvericin
• Synonymes: Cyclo[(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-phenylalanyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-phenylalanyl-(2R)-2-hydroxy -3-methylbutanoyl-N-methyl-L-phenylalanyl], Cyclo(-D-.alpha.-hydroxyisovaleryl-N-Me-Phe)3, (3S,6R,9S,12R,15S,18R)-3,9,15-tribenzyl-4,10,16-trimethyl-6,12,18-tris(1-methylethyl)-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone
• CAS: 26048-05-5

Description

Beauvericin is a cyclic peptide that is isolated from the fungus Fusarium. It has been shown to have antimicrobial activity against bacteria, as well as a variety of other biological properties. Beauvericin has been shown to inhibit mitochondrial membrane potential and induce toxicity in some animal models. Beauvericin also inhibits protein synthesis and causes cell death by inhibiting DNA polymerase activity. This compound is active against cancer cells, including HL-60 cells, which are derived from human lymphocytes and are used as a model for leukemia. Beauvericin can be extracted from an ETOA extract of the fungus Fusarium oxysporum; this extract has shown anti-cancer effects in vitro assays.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 783.95 g/mol
• Formule: C₄₅H₅₇N₃O₉
• Degré de pureté: Min. 95%